DIFFERENT RESPONSES OF BONE AND ARTICULAR TISSUE OF WISTAR RATS, SUBMITTED TO EXERCISE RESISTED, AFTER NERVOUS INJURY

Abstract

Objective: To analyze the effect of resistance exercise climb stairs in bone tissue and articular after compression injury of the sciatic nerve of Wistar rats. Methods: 32 rats were randomly divided into 4 groups with 8 animals in each, G1 (control), G2 (exercise), G3 (injury) and G4 (injury and exercise). After nerve injury G2 and G4 were submitted to resistance exercise climb stairs, for 5 days a week, with two days interval for 21 days. After the experiment, the animals were euthanized and the knee and tibia of the injured hindlimb were collected, and followed the standard processing for analysis by light microscopy. ResultsThe bone tissue change significantly in relation to morphometric analysis of the area of the spinal canal and counting and osteocytes, however, was not observed significant difference in the analysis of the thickness of the cortical bone.  A joint tissue were observed discrete morphological changes between the groups. Conclusion: The sciatic nerve injury in rats brought deleterious effects on bone tissue and articular. It was also observed that resistance exercise in stair climbing brought no changes to bone tissue of animals, however, it was effective to return to the normal characteristics of the injured joint, and showed increased evidence of tidemark in uninjured animals.