PATHOPHYSIOLOGY OF POSTURAL HYPOTENSION AND ORTHOSTATIC INTOLERANCE

Abstract

Introduction: Phenomena of postural hypotension and orthostatic intolerance result from situations involving transient cerebral hypoflow and are usually related to a benign and amenable condition, whether pharmacological or not. Objective: To discuss the physiopathological aspects involved in the episodes of loss of consciousness related to the cardiovascular system. Methodology: A literature review was developed containing articles in English and Portuguese and chapters of books that address pathophysiological aspects in postural hypotension or orthostatic intolerance. Results / Discussion: Benign cases of syncope associated with the cardiovascular system, mainly recurrent ones, have complex pathophysiology, and it is necessary to understand the mechanisms involved in the episodes of loss of consciousness in order to develop better pharmacological or Not to approach the patients involved. Situations with autonomic dysregulation are invariably present in the genesis of syncopal episodes. Final considerations: The pathophysiology related to the loss of consciousness associated with the cardiovascular system involves factors such as preexisting diseases, drug use, aging, exercise intensity and others, which should be considered by the healthcare professional involved in the care process for this population.