Efeitos do treinamento intervalado de alta intensidade e do treinamento combinado associado à terapia de fotobiomodulação em pacientes diabéticos do tipo 2 (DT2): protocolo para um estudo controlado randomizado

Autores

DOI:

https://doi.org/10.17267/2238-2704rpf.2022.e4424

Palavras-chave:

Diabetes mellitus tipo 2, Controle glicêmico, Treinamento Intervalado de Alta Intensidade, Terapia com Luz de Baixa Intensidade, Qualidade de vida

Resumo

INTRODUÇÃO: O diabetes tipo 2 (DT2) pode ser responsável por disfunção cardiometabólica e redução da qualidade de vida (QV) devido ao seu impacto negativo na capacidade funcional de exercício. OBJETIVO: Investigar os efeitos de diferentes tipos de treinamento físico [treinamento intervalado de alta intensidade (TIAI) e treinamento combinado (TC)] associado à terapia com diodo emissor de luz (LED) no status cardiometabólico, capacidade funcional e QV em pacientes com DT2. MÉTODOS: Estudo controlado randomizado que será realizado em laboratório universitário de reabilitação cardiopulmonar com pessoas da comunidade com diagnóstico confirmado de DT2, idade 18 anos e sedentários nos últimos seis meses. Os participantes serão alocados aleatoriamente para um dos seis grupos: TIAI com e sem terapia LED, TC com e sem terapia LED, grupo controle com e sem terapia LED. O protocolo de treinamento deve ser realizado por 12 semanas, 3 vezes na semana em dias alternados, totalizando 36 sessões de treinamento. O desfecho primário será a capacidade de exercício e o controle glicêmico. Os desfechos secundários serão QV, função endotelial, função musculoesquelética, modulação autonômica cardíaca e composição corporal. Os resultados serão medidos antes e após 12 semanas de treinamento. Para análise estatística será utilizado o programa SPSS® 19.0. O nível de significância adotado será p0,05. PERSPECTIVAS: Os resultados deste estudo têm o potencial de fornecer informações importantes sobre os efeitos de diferentes tipos de treinamento físico associados à terapia com LED e podem apoiar o uso dessa combinação terapêutica em pacientes com DT2, melhorando sua saúde geral.

 

Downloads

Os dados de download ainda não estão disponíveis.

Referências

(1) Wild S, Roglic G, Green A, Sicree R, King H. Global prevalence of diabetes: estimates for the year, and projections for 2030. Diab Car. 2004;2 (5):1047–1053. https://doi.org/10.2337/diacare.27.5.1047

(2) Schmidt MI, Duncan BB, Azevedo e Silva G, Menezes AM, Monteiro CA, Barreto SM, et al. Chronic non-communicable diseases in Brazil: burden and current challenges. Lancet. 2011;377(9781):1949–1961. https://doi.org/10.1016/S0140-6736(11)60135-9

(3) Stanford KI, Goodyear LJ. Exercise and type 2 diabetes: molecular mechanisms regulating glucose uptake in skeletal muscle. Adv Physiol Educ. 2014;38(4):308-314. https://doi.org/10.1152/advan.00080.2014

(4)Bertoluci MC, Rocha VZ. Cardiovascular risk assessment in patients with diabetes. Diabetol Metab Syndr. 2017;9(25). https://doi.org/10.1186/s13098-017-0225-1

(5)Abdul-Ghani M, DeFronzo RA, Prato SD, Chilton R, Singh R, Ryder REJ. Cardiovascular Disease and Type 2 Diabetes: Has the Dawn of a New Era Arrived? Diabetes Care. 2017;40(7):813–820. https://doi.org/10.2337/dc16-2736

(6) Seyoum B, Estacio RO, Berhanu P, Schrier RW. Exercise capacity is a predictor of cardiovascular events in patients with type 2 diabetes mellitus. Diab Vasc Dis Res. 2006;3(3):197–201. https://doi.org/10.3132/dvdr.2006.030

(7) Nadeau KJ, Zeitler PS, Bauer TA, Brown MS, Dorosz JL, Draznin B, et al. Insulin resistance in adolescents with type 2 diabetes is associated with impaired exercise capacity. J Clin Endocrinol Metab. 2009;94(10):3687–3695. https://doi.org/10.1210/jc.2008-2844

(8) Francisco CO, Catai AM, Moura-Tonello SC, Lopes SL, Benze BG, Del Vale AM, et al. Cardiorespiratory fitness, pulmonary function and C-reactive protein levels in nonsmoking individuals with diabetes. Braz J Med Biol Res. 2014;47(5):426–431. https://doi.org/10.1590/1414-431X20143370

(9) Brassard P, Ferland A, Bogaty P, Desmeules M, Jobin J, Poirier P. Influence of glycemic control on pulmonary function and heart rate in response to exercise in subjects with type 2 diabetes mellitus. Metabolism. 2006;55(11):1532-7. https://doi.org/10.1016/j.metabol.2006.06.025

(10) Góralczyk K, Szyma?ska J, Szot K, Fisz J, Ro?? D. Low-level laser irradiation effect on endothelial cells under conditions of hyperglycemia. Lasers Med Sci. 2016;31:825–831.https://doi.org/10.1007/s10103-016-1880-4

(11) Vincent AM, Edwards JL, McLean LL, Hong Y, Cerri F, Lopez I, et al. Mitochondrial biogenesis and fission in axons in cell culture and animal models of diabetic neuropathy. Acta Neuropathol. 2010;120(4):477-89. https://doi.org/10.1007/s00401-010-0697-7

(12) Chen L, Pei J-H, Kuang J, Chen H-M, Chen Z, Li Z-W, et al. Effect of lifestyle intervention in patients with type 2 diabetes: a meta-analysis. Metabolism. 2015;64(2):338–347. https://doi.org/10.1016/j.metabol.2014.10.018

(13) Boulé NG, Haddad E, Kenny GP, Wells GA, Sigal RJ. Effects of exercise on glycemic control and body mass in type 2 diabetes mellitus: a meta-analy¬sis of controlled clinical trials. JAMA. 2001;286(10):1218–1227. https://doi.org/10.1001/jama.286.10.1218

(14) Bassi D, Mendes RG, Arakelian VM, Caruso FCR, Cabiddu R, Bonjorno-Júnior JC, et al. Potential Effects on Cardiorespiratory and Metabolic Status After a Concurrent Strength and Endurance Training Program in Diabetes Patients — a Randomized Controlled Trial. Sports Med Open. 2016; 2:31. https://doi.org/10.1186/s40798-016-0052-1

(15) Francois ME, Little JP. Effectiveness and Safety of High-Intensity Interval Training in Patients With Type 2 Diabetes. Diabetes Spectrum. 2015; 28(1): 39-44. https://doi.org/10.2337/diaspect.28.1.39

(16) Colberg SR, Sigal RJ, Fernhall B, Regensteiner JG, Blissmer BJ, Rubin RR, et al. Exercise and type 2 diabetes: the American College of Sports Medicine and the American Diabetes Association: joint position statement executive summary. Diabetes Care. 2010;33(12):e147-67. https://doi.org/10.2337/dc10-9990

(17) Huang YY, Sharma SK, Carroll J, Hamblin MR. Biphasic Dose Response in Low Level Light Therapy - An Update. Dose-Response. 2011;9(4):602-618. https://doi.org/10.2203/dose-response.11-009.Hamblin

(18) Lizarelli RFZ, Miguel FAC, Freitas-Pontes KM, Villa GEP, Nunez SC, Bagnato VS. Dentin hypersensitivity clinical study comparing LILT and LEDT keeping the same irradiation parameters. Laser Physics Letters [Internet]. 2010;7(11):805-811. Available from: http://repositorio.ipen.br/handle/123456789/26635

(19) Ferraresi C, Santos RV, Marques G, Zangrande M, Leonaldo R, Hamblin MR, et al. Light-emitting diode therapy (LEDT) before matches prevents increase in creatine kinase with a light dose response in volleyball players. Lasers Med Sci. 2015;30(4):1281-1287. https://doi.org/10.1007/s10103-015-1728-3

(20) Miranda EF, Vanin AA, Tomazoni SS, Grandinetti VS, Paiva PRV, Machado CSM, et al. Using Pre-Exercise Photobiomodulation Therapy Combining Super-Pulsed Lasers and Light-Emitting Diodes to Improve Performance in Progressive Cardiopulmonary Exercise Tests. J Athl Train. 2016;51(2):129–135. https://doi.org/10.4085/1062-6050-51.3.10.

(21) Miranda EF, Leal ECP Jr, Marchetti PH, Corso SD. Acute effects of light emitting diodes therapy (LEDT) in muscle function during isometric exercise in patients with chronic obstructive pulmonary disease: preliminary results of a randomized controlled trial. Lasers Med Sci. 2014;29(1):359-365. https://doi.org/10.1007/s10103-013-1359-5

(22) Adamskaya N, Dungel P, Mittermayr R, Hartinger J, Feichtinger G, Wassermann K, et al. Light therapy by blue LED improves wound healing in an excision model in rats. Injury. 2011;42(9):917-921. https://doi.org/10.1016/j.injury.2010.03.023

(23) Haskell WL, Lee IM, Pate RR, Powell KE, Blair SN, Franklin BA, et al. Physical activity and public health: updated recommendation for adults from the American College of Sports Medicine and the American Heart Association. Med Sci Sports Exerc. 2007 Aug;39(8):1423-34. https://doi.org/10.1249/mss.0b013e3180616b27.

(24) Sigal RJ, Kenny GP, Wasserman DH, Castaneda-Sceppa C, White RD. Physical activity/exercise and type 2 diabetes: a consensus statement from the American Diabetes Association. Diabetes Care. 2006;29(6):1433–1438. https://doi.org/10.2337/dc06-9910

(25) Borg GA. Psychophysical bases of perceived exertion. Med Sci Sports Exerc. 1982;14(5):377-381. Cited: PMID: 7154893.

(26) Leal EC Jr, Vanin AA, Miranda EF, Carvalho PT, Corso SD, Bjordal JM. Effect of phototherapy (low-level laser therapy and light-emitting diode therapy) on exercise performance and markers of exercise recovery: a systematic review with meta-analysis. Lasers Med Sci. 2015;30(2):925-939. https://doi.org/10.1007/s10103-013-1465-4

(27) Ferraresi C, Hamblin MR, Parizotto NA. Low-level laser (light) therapy (LLLT) on muscle tissue: performance, fatigue and repair benefited by the power of light. Photonics Lasers Med. 2012;1(4):267-286. https://doi.org/10.1515/plm-2012-0032

(28) Costa IP, Politti F, Cahalin LP, Carvalho EFT, Costa D, Corrêa JCF, et al. Acute Effects Using Light-Emitting Diode Therapy (LEDT) for Muscle Function during Isometric Exercise in Asthma Patients: A Pilot Study. BioMed Research International. 2019;2019. https://doi.org/10.1155/2019/7501870.

(29) Ferraresi C, Beltrame T, Fabrizzi F, Nascimento ESP, Karsten M, Francisco CO, et al. Muscular pre-conditioning using light-emitting diode therapy (LEDT) for high-intensity exercise: a randomized double-blind placebo-controlled trial with a single elite runner. Physiother Theory Pract. 2015;31(5):354-361. https://doi.org/10.3109/09593985.2014.1003118

(30) Singh SJ, Morgan MD, Scott S, Walters D, Hardman AE. Development of a shuttle walking test of disability in patients with chronic airways obstruction. Thorax. 1992;47(12):1019-1024. https://doi.org/10.1136/thx.47.12.1019

(31) Thijssen DH, Black MA, Pyke KE, Padilla J, Atkinson G, Harris RA, et al. Assessment of flow-mediated dilation in humans: a methodological and physiological guideline. Am J Physiol Heart Circ Physiol. 2011;300(1):H2-12. https://doi.org/10.1152/ajpheart.00471.2010

(32) Gibbs BB, Dobrosielski DA, Bonekamp S, Stewart KJ, Clark JM. A randomized trial of exercise for blood pressure reduction in type 2 diabetes: effect on flow-mediated dilation and circulating biomarkers of endothelial function. Atherosclerosis. 2012;224(2): 446–453. https://doi.org/10.1016/j.atherosclerosis.2012.07.035

(33) Madsen SM, Thorup AC, Overgaard K, Bjerre M, Jeppesen PB. Functional and structural vascular adaptations following 8 weeks of low volume high intensity interval training in lower leg of type 2 diabetes patients and individuals at high risk of metabolic syndrome. Arch Physiol Biochem. 2015;121(5):178-186. https://doi.org/10.3109/13813455.2015.1087033

(34) Matsudo S, Araujo T, Matsudo V, Andrade D, Andrade E, Oliveira LC, et al. Questionário Internacional de Atividade Física (IPAQ): Estudo de validade e reprodutibilidade no Brasil. Rev Bras Atividade Física e Saúde. 2001;6(2):5-18. https://doi.org/10.12820/rbafs.v.6n2p5-18

(35) Craig CL, Marshall AL, Sjöström M, Bauman AE, Booth ML, Ainsworth BE, et al. International physical activity questionnaire: 12-country reliability and validity. Med Sci Sports Exerc. 2003;35(8):1381-1395. https://doi.org/10.1249/01.MSS.0000078924.61453.FB

(36) Ciconelli RM, Ferraz MB, Santos W, Meinão I, Quaresma MR. Tradução para língua portuguesa e validação do questionário genérico de avaliação de qualidade de vida SF-36 (Brasil SF-36). Rev Bras Reumatol. [Internet] 1999; 39(3):143-150. Available from: https://www.ufjf.br/renato_nunes/files/2014/03/Valida%C3%A7%C3%A3o-do-Question%C3%A1rio-de-qualidade-de-Vida-SF-36.pdf

(37) Terada T, Friesen A, Chahal BS, Bell GJ, McCargar LJ, Boule NG. Feasibility and preliminary efficacy of high intensity interval training in type 2 diabetes. Diabetes Res Clin Pract. 2013;99(2):120-129. https://doi.org/10.1016/j.diabres.2012.10.019

Publicado

02.08.2022

Edição

Seção

Métodos & Protocolos

Como Citar

Efeitos do treinamento intervalado de alta intensidade e do treinamento combinado associado à terapia de fotobiomodulação em pacientes diabéticos do tipo 2 (DT2): protocolo para um estudo controlado randomizado. (2022). Revista Pesquisa Em Fisioterapia, 12, e4424. https://doi.org/10.17267/2238-2704rpf.2022.e4424

Artigos mais lidos pelo mesmo(s) autor(es)

1 2 3 4 5 6 7 8 9 10 > >>