Complications after a kidney transplant and impact on hospitalization time
DOI:
https://doi.org/10.17267/2317-3378rec.2025.e6280Keywords:
Nursing, Patient Discharge, Kidney TransplantationAbstract
OBJECTIVE: To evaluate post-kidney transplant complications and their repercussions on the duration of hospital stay. METHODOLOGY: This is a descriptive, documentary, retrospective and quantitative study, carried out in a public reference hospital. The sample consisted of 255 medical records of patients over 18 years of age who had undergone kidney transplantation for more than six months. Cases of double transplantation were excluded. RESULTS: Most patients were between 40 and 59 years old (42%), male (58.4%) and had a normal BMI (41.2%). Surgical complications, infections, and changes in graft function were significantly associated. The median hospital stay was 33 days for patients with surgical complications, compared to 10 days for the others (p<0.001). In cases of nonspecific infection, the median time was 25 days (p<0.001). The most prevalent infection was urinary tract, with a median length of hospital stay of 31 days. Patients with immediate graft function had a median hospital stay of 7 days; slow function, 10 days; late function, 20 days; and graft loss, 35 days. CONCLUSIONS: After the evaluation of complications after kidney transplantation, a significant association was observed with the length of hospital stay, the presence of UTI had a negative impact on the prognosis and the evolution of postoperative recovery.
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1. Abramyan S, Hanlon M. Kidney Transplantation. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025. Available from: https://www.ncbi.nlm.nih.gov/books/NBK567755/
2. Starck É, Mittelmann TH, Lovatto MVP, Nakalski LR, Abate DTRS. Infectious Complications in the First Year Post Renal Transplantation. Braz J of Develop. 2020;6(6):36663–76. https://doi.org/10.34117/bjdv6n6-270
3. Bonando BM, Freitas FSS, Gobbi V, Silva BSF, Vitorino LM, Torres JHG. Postoperative Complications in Kidney Transplant Patients at a Transplant Center in the South of Minas Gerais. Braz J Transpl. 2024;27:e3424. https://doi.org/10.53855/bjt.v27i1.586_PORT
4. Silva AR, Barbosa FMA, Costa PQ, Rocha CM, Branco KMPC, Silva Junior GB, et al. Perception of renal transplant patients about immunosuppressive pharmacotherapy: perspectives and difficulties. REAS/EJCH. 2020;(53):e3768. https://doi.org/10.25248/reas.e3768.2020
5. Carminatti M, Tedesco-Silva H, Fernandes NMS, Sanders-Pinheiro H. Chronic kidney disease progression in kidney transplant recipients: A focus on traditional risk factors. Nephrology. 2019;24(2):141–7. http://doi.org/10.1111/nep.13483
6. Blichová T, Kleinová P, Vnučák M, Graňák K, Kollár A, Svihra J Jr, et al. Surgical complications after kidney transplantation. Ann Transplant. 2025;30:e948531. http://doi.org/10.12659/AOT.948531
7. Ecker R, Beltrame V, Dallacosta FM. Kidney post-transplant mortality. RIES [Internet]. 2019;8(2):253–60. Available from: https://periodicos.uniarp.edu.br/index.php/ries/article/view/1544
8. Saad EJ, Fernández P, Azua AEC, Ellena V, Diz C, Giordano G, et al. Infections in the first year after renal transplant. Medicina [Internet]. 2020;80(6):611-21. Available from: https://www.medicinabuenosaires.com/PMID/33254105.pdf
9. Nascimento AM, Boehm IG, Peixoto EM, Dias GG, Barbosa GC, Tostes IF, et al. Complications after kidney transplantation. REAC. 2023;43:e11990. https://doi.org/10.25248/reac.e11990.2023
10. Alves EBS, Fernandes AMG, Mendonça AEO, Costa RTS, Souza Neto VL, Pinheiro MB. Main causes of kidney rejection in transplant patients. Rev enferm UFPI [Internet]. 2019;8(3):78–82. Available from: https://pesquisa.bvsalud.org/portal/resource/pt/biblio-1364009
11. Silva ECS, Guilherme SP, Miranda CN, Alvim ALS, Ferreira GF, Nascimento TC, et al. Occurrence of Urinary Tract Infection in Patients After Kidney Transplantation. Braz J Transplant. 2025;28:e0425. https://doi.org/10.53855/bjt.v28i1.649_PORT
12. Cockwell P, Fisher LA. The global burden of chronic kidney disease. Lancet. 2020;395(10225):662–4. https://doi.org/10.1016/S0140-6736(19)32977-0
13. Hulley SB, Cummings SR, Browner WS, Grady DG, Newman TB. Designing clinical research [Internet]. 4th ed. Porto Alegre: Artmed; 2015. Available from: https://www.biosanas.com.br/uploads/outros/artigos_cientificos/143/c4fd11a995cc235510d275cf8298427d.pdf
14. Barros EB, Ribeiro CH, Pinto IRMP, Itapary PGAP, Paiva LDT, Moura VR, et al. Kidney transplantation: advances, challenges and long-term results: integrative review. Periódicos Brasil. Pesquisa Científica. 2023;5(3):1394-402. https://doi.org/10.36557/pbpc.v3i2.180
15. Barretto LP. Evaluation of changes in nutritional status and body composition in the development of diabetes mellitus after kidney transplantation [Dissertação de Mestrado] [Internet]. São Paulo: Universidade de São Paulo; 2019. https://doi.org/10.11606/D.17.2019.tde-12072019-083020
16. Campos CS, Santos KB, Ferreira GF, Bastos KV. Perfil epidemiológico dos pacientes em lista única de espera para transplante renal na Cidade de Juiz de Fora. HU Revista [Internet]. 2017;43(3):407–13. Available from: https://periodicos.ufjf.br/index.php/hurevista/article/view/2955/pdf
17. Lins SMSB, Leite JL, Godoy S, Tavares JMAB, Rocha RG, Silva FVC. Treatment adherence of chronic kidney disease patients on hemodialysis. Acta Paul Enferm. 2018;31(1):54–60. https://doi.org/10.1590/1982-0194201800009
18. Marinho AWGB, Galvão TF, Silva MT. Prevalence of self-reported chronic kidney disease in adults in the Metropolitan Region of Manaus: a cross-sectional population-based study, 2015. Epidemiol Serv Saúde. 2020;29(1):e2019122. https://doi.org/10.5123/S1679-49742020000100003
19. Sugünes N, Bichmann A, Biernath N, Peters R, Budde K, Liefeldt L, et al. Analysis of the Effects of Day-Time vs. Night-Time Surgery on Renal Transplant Patient Outcomes. J Clin Med. 2019;8(7):1051. http://doi.org/10.3390/jcm8071051
20. Santos LF, Prado B da C, Castro FP dos S, Brito RF, Maciel SC, Avelar TC. Quality of Life in Kidney Transplant Patients. Psico-USF. 2018;23:163–72. https://doi.org/10.1590/1413-82712018230114
21. Fu R, Kim SJ, Oliveira C, Coyte PC. An instrumental variable approach confirms that the duration of pretransplant dialysis has a negative impact on the survival of kidney transplant recipients and quantifies the risk. Kidney International [Internet]. 2019;96(2):450–9. Available from: https://www.kidney-international.org/article/S0085-2538(19)30323-0/fulltext
22. Nerbass FB, Lima HN, Thomé FS, Vieira Neto OM, Sesso R, Lugon JR. Brazilian Dialysis Survey 2021. Braz J Nephrol [Internet]. 2023;45(2):193–9. Available from: https://www.scielo.br/j/jbn/a/FPDbGN5DHWjvMmRS98mH5kS/?format=pdf&lang=pt
23. Oliveira LSV. Sociodemographic and clinical profile of patients with kidney transplantation and the factors associated with rejection of the transplanted organ in a philanthropic hospital in Florianópolis [Conclusion paper] [Internet]. Palhoça: Universidade do Sul de Santa Catarina; 2020. Available from: https://repositorio.animaeducacao.com.br/handle/ANIMA/4886
24. Lores JC, Ecker R, Lavarda SCS. Kidney transplantation: relating type of graft and ischemia time. Rev enferm UFPE [Internet]. 2019;13(5):1405–11. Available from: https://pesquisa.bvsalud.org/portal/resource/pt/biblio-1024517
25. Schiavelli R, Ajzenszlos M, Tullio DD, Campoverde NR, Maiolo E, Margulis F, et al. Multidrug-resistant microorganisms causing urinary infections in hospitalized patients with renal transplant. Rev Nefrol Dial Traspl [Internet]. 2019;39(1):15-25. Available from: http://revistarenal.org.ar/index.php/rndt/article/view/402
26. Jahn L, Rüster C, Schlosser M, Winkler Y, Foller S, Grimm MO, et al. Rate, Factors, and Outcome of Delayed Graft Function After Kidney Transplantation of Deceased Donors. Transplantation Proceedings. 2021;53(5):1454–61. http://doi.org/10.1016/j.transproceed.2021.01.006
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Copyright (c) 2025 Amanda Maria Bezerra Rocha, Maria Isabele Lopes Severiano de Sousa, Lucas Mendes Feitosa Dias, Rita Mônica Borges Studart
This work is licensed under a Creative Commons Attribution 4.0 International License.
This work is licensed under a Creative Commons Attribution 4.0 International License.
