HPV vaccines for prevention of cervical pre-cancer in adolescent girls and women

Authors

  • Jia Jian Li Department of Emergency Medicine, State University of New York, Downstate Medical Center, Brooklyn, New York, USA http://orcid.org/0000-0002-4446-9412
  • Jessica Stetz Department of Emergency Medicine, State University of New York, Downstate Medical Center, Brooklyn, New York, USA

DOI:

https://doi.org/10.17267/2675-021Xevidence.v1i2.2510

Keywords:

HPV, Vaccines, Cervical pre-cancer, cervical cancer, adolescent

Abstract

The evidence presented in this Cochrane meta-analysis shows the HPV vaccination confers significant benefit in preventing cervical pre-cancer. NNT of 60 for preventing one cervical pre-cancer (women 15 to 25 years old with or without HPV infection). The effect is higher for lesions associated with HPV16/18. The data also demonstrates an absence of serious adverse events. Therefore, we have assigned a color recommendation of Green (Benefit > Harm) to this vaccine.

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Author Biography

  • Jessica Stetz, Department of Emergency Medicine, State University of New York, Downstate Medical Center, Brooklyn, New York, USA
    Attending Physiican in Emergency Medicine

References

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Available at https://www.cancer.org/cancer/cancer-basics/lifetime-probability-of-developing-or-dying-from-cancer.html. Last accessed on November 30,2018

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Initiative for Vaccine Research of the Department of Immunization Vaccines and Biologicals (WHO). Human Papillomavirus (HPV) Vaccine Background Paper. World Health Organization (WHO) 2009:1–249.

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Available at: https://www.goodrx.com/gardasil-9?drug-name=gardasil+9. Last accessed December 1st, 2018.

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Published

10/21/2019

Issue

Vol. 1 No. 2 (2019)

Section

Critical Appraisal of Evidence

License

The authors retain copyrights, transferring to the Journal of Evidence-Based Healthcare only the right of first publication. This work is licensed under a Creative Commons Attribution 4.0 International License.

Creative Commons License

How to Cite

HPV vaccines for prevention of cervical pre-cancer in adolescent girls and women. (2019). Journal of Evidence-Based Healthcare, 1(2), 112-115. https://doi.org/10.17267/2675-021Xevidence.v1i2.2510

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