MICROALBUMINURIA IS NOT ASSOCIATED WITH ENDOTHELIAL DYSFUNCTION IN OBESE AND OVERWEIGHT WOMEN, BUT IS STRONGLY CORRELATED WITH FASTING GLYCEMIA

Autores

  • Rômulo Bagano Menezes Bahiana School of Medicine and Public Health
  • Raphael Ribeiro Sampaio Bahiana School of Medicine and Public Health
  • Armênio Guimarães Bahiana School of Medicine and Public Health
  • Lucas Lima Olivieri Bahiana School of Medicine and Public Health
  • Maria de Lourdes Lima Bahiana School of Medicine and Public Health
  • Ana Marice Ladeia Bahiana School of Medicine and Public Health

DOI:

https://doi.org/10.17267/2317-3386bjmhh.v1i2.239

Palavras-chave:

Obesity, Endothelial dysfunction, Microalbuminuria, Atherosclerosis, Flow-mediated dilation

Resumo

This study aimed to evaluate the association between endothelial dysfunction and microalbuminuria levels in overweight and obese women. Methods: This cross-sectional study analyzed secondary data of patients with BMI ? 25 Kg/m2 who had microalbuminuria and endothelial function test already performed and inserted into the survey database. The endothelial function was evaluated by reactive hyperemia test (endothelium-dependent vasodilation). Results: This study included 41 women aged of 53 ­± 11 years, BMI of 32.56 ± 5.06 Kg/m2, WC  of 100.36 ± 23.21 cm. There was no correlation between microalbuminuria and endothelial function. A multivariate logistic regression analysis identified   glucose fasting (? = 0.804; p < 0,00,1) and HDL (? = - 0.309; p = 0.048) levels  as independent predictors of microalbuminuria. Conclusion: Microalbuminuria is not useful as a marker of subclinical atherosclerosis in this population, however can be associated to glucose fasting and HDL levels.

Biografia do Autor

  • Rômulo Bagano Menezes, Bahiana School of Medicine and Public Health

    Medical Student, Bahiana School of Medicine  and Public Health, Salvador, Bahia, Brazil.

  • Raphael Ribeiro Sampaio, Bahiana School of Medicine and Public Health

    Medical Student, Bahiana School of Medicine and Public Health, Salvador, Bahia, Brazil.

  • Armênio Guimarães, Bahiana School of Medicine and Public Health

    PhD, Full professor, Bahiana School of Medicine and Public Health, Salvador, Bahia, Brazil.

  • Lucas Lima Olivieri, Bahiana School of Medicine and Public Health

    Medical Student, Bahiana School of Medicine and Public Health, Salvador, Bahia, Brazil.

  • Maria de Lourdes Lima, Bahiana School of Medicine and Public Health

    PhD, Adjunct professor, Bahiana School of Medicine and Public Health, Salvador, Bahia, Brazil.

  • Ana Marice Ladeia, Bahiana School of Medicine and Public Health

    PhD, Full professor, Bahiana School of Medicine and Public Health, Salvador, Bahia, Brazil.

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Publicado

2013-09-07

Edição

Seção

Bahiana School of Medicine and Public Health's Research Groups Brief Report