BULLOUS ERYTHEMA NODOSUM AS INITIAL MANIFESTATION OF LEPROSY

Autores

  • Carlos Antônio Gusmão Guerreiro Moura Sister Dulce's Social Works - Santo Antônio's Hospital. Bahiana School of Medicine and Public Health.
  • Raphael Sampaio Sister Dulce's Social Works - Santo Antônio's Hospital.
  • Paulo Góes Sister Dulce's Social Works - Santo Antônio's Hospital.
  • Gabriel de Magalhães Freitas Bahiana School of Medicine and Public Health.
  • Constança Margarida Sampaio Cruz Sister Dulce's Social Works - Santo Antônio's Hospital. Bahiana School of Medicine and Public Health.
  • Carlos Geraldo Guerreiro Moura Sister Dulce's Social Works - Santo Antônio's Hospital. Bahiana School of Medicine and Public Health.

DOI:

https://doi.org/10.17267/2317-3386bjmhh.v5i3.1461

Palavras-chave:

Hansen disease, leprosy, mycobacterium, Bullous erythema nodosum

Resumo

Introduction: Leprosy is a chronic granulomatous infectious disease caused by Mycobacterium leprae with protean manifestations, particularly prone to affect skin and peripheral nerves. The natural course of the disease may be associated with the development of type 1 or type 2 immunologic reactions. These immunologic reactions are reported to be caused by increased activity of the immune system, particularly a cell-mediated immune response against live leprosy bacillus or remnants of dead bacilli. Leprosy is one of the oldest diseases of mankind. Its clinical diagnosis can be challenging due to the varied manifestations. The first description of bullous erythema nodosum was made 1898 and since then there are few recorded reports. Case Report: Here we present a case of bullous erythema nodosum as leprosy first manifestation. A 35 year-woman presented with 1-year history of disseminated blisters on trunk, forearms and thighs, and multiple painful ulcerated nodules on her face. She reported that the lesions in her face became eroded and ulcerated spontaneously. There were no thickened nerves. Blood and Histopathological investigations were made. The treatment instituted was prednisone 1mg/kg without thalidomide. After two weeks with excellent response, specific therapy for Mycobacterium leprae was initiated by the infectious diseases assistant physician with a satisfactory response.

Biografia do Autor

Carlos Antônio Gusmão Guerreiro Moura, Sister Dulce's Social Works - Santo Antônio's Hospital. Bahiana School of Medicine and Public Health.

Department: Program of Residence of Medical Clinic of the Santo Antonio's Hospital, Sister Dulce's Social Works, Salvador, Brazil.

Postgraduate course of medicine and Human Health of Bahiana School of Medicine and Public Health.

rank: MD

Raphael Sampaio, Sister Dulce's Social Works - Santo Antônio's Hospital.

Department: Program of Residence of Medical Clinic of the Santo Antonio's Hospital, Sister Dulce's Social Works, Salvador, Brazil.

 

rank: MD

Paulo Góes, Sister Dulce's Social Works - Santo Antônio's Hospital.

Department: Program of Residence of Medical Clinic of the Santo Antonio's Hospital, Sister Dulce's Social Works, Salvador, Brazil.

 

rank: MD

Gabriel de Magalhães Freitas, Bahiana School of Medicine and Public Health.

Department: Program of scientific initiation of Bahiana School of Medicine and Public Health.

rank: Medical Student of Bahiana School of Medicine and Public Health

Constança Margarida Sampaio Cruz, Sister Dulce's Social Works - Santo Antônio's Hospital. Bahiana School of Medicine and Public Health.

Department: Program of Residence of Medical Clinic of the Santo Antonio's Hospital, Sister Dulce's Social Works, Salvador, Brazil.

Postgraduate course of medicine and Human Health of Bahiana School of Medicine and Public Health.

rank: MD, PhD

Carlos Geraldo Guerreiro Moura, Sister Dulce's Social Works - Santo Antônio's Hospital. Bahiana School of Medicine and Public Health.

Department: Program of Residence of Medical Clinic of the Santo Antonio's Hospital, Sister Dulce's Social Works, Salvador, Brazil.

Postgraduate course of medicine and Human Health of Bahiana School of Medicine and Public Health.

rank:MD, PhD

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Publicado

2017-09-29

Edição

Seção

Case Reports